Achievements

2024

2: Makabe K, Ishida N, Kanezaki N, Shiono Y, Koseki T. Aspergillus oryzae α-l-

rhamnosidase: Crystal structure and insight into the substrate specificity.

Proteins. 2024 Feb;92(2):236-245.

1:Cytotoxic constituents from the fruit of Solanum aculeastrum

Nadine-Phalone Tinguep Tchapnda, Ruth Bibiane Njinkou Njambouo, Marguerite Hortence Tchuendem Kenmogne, Pascal Djimeli Douanla, Yoshihito Shiono & Turibio Kuiate Tabopda

Received 29 Apr 2023, Accepted 12 Feb 2024, Published online: 26 Feb 2024

Natural Product Research



2023

10: T.Koseki, et al., Aspergillus oryzae α-L-rhamnosidase: crystal structure and insight into the substrate specificity

 PROTEINS (accepted)

9:  Sofian, FF, Kurniawati, N, Yoshida, J, Ito, Y, Tchoukoua, A, Tabopda, TK, Lannang, AM, Ngadjui, BT, Koseki, T, Shiono, Y. 2023. New fatty acid ester and meroterpenoid produced by the endophytic fungus Penicillium sp. NR-1. Phytochemistry Letters, 56, 5-12. DOI: 10.1016/j.phytol.2023.05.013

8:  Kamdeu EN, Menye Nomo AN, Tchoukoua A, Ngomo O, Djimeli Douanla P, Tchuendem

Kenmogne MH, Shiono Y, Tabopda TK. 

Schweinfurthiamide, a new alkaloid isolated

from the tuber roots of <i>Asparagus flagellaris</i> Baker (Liliaceae). Nat Prod Res. 2023 Sep 18:1-7. doi: 10.1080/14786419.2023.2257358. Epub ahead of print.


7: Atakuru Paulin D, Koseki T, Usukhbayar N, Kimura KI, Shiono Y. 

Cytotoxicity and induction of G1 phase cell cycle arrest in human acute promyelocytic leukemia HL60 cells by indole alkaloids isolated from Dialium corbisieri seeds.

Biosci Biotechnol Biochem. 2023 Jul 24;87(8):825-832. doi: 10.1093/bbb/zbad067.

6: Pentandricines F-H, cytotoxic limonoids from the stem bark of Chisocheton pentandrus (Blanco) Merr

Desi Harneti, Supriatno Salam c, Nurlelasari, Rani Maharani, Tri Mayanti, Agus Safari, Ace Tatang Hidayat, Ronny Lesmana, Sofa Fajriah, Unang Supratman, Thomas Prescott, Yoshihito Shiono, Phytochemistry Letter Volume 54, April 2023, Pages 119-124

5. Okuda C, Ueda Y, Muroi M, Sanada E, Osada H, Shiono Y, Kimura KI, Takeda K, Kawaguchi K, Kataoka T. Allantopyrone A interferes with the degradation of hypoxia-inducible factor 1α protein by reducing proteasome activity in human fibrosarcoma HT-1080 cells. J Antibiot (Tokyo). 2023 Mar 30. doi:10.1038/s41429-023-00610-5. Epub ahead of print. PMID: 36997727.

4.Polyketides isolated from endophyte Fusarium armeniacum and their cytotoxic activities

Shiho Sato, Ferry Ferdiansyah Sofian, Dradre Atakuru Paulin, Sho Kobayashi, Takuya Koseki, Yoshihito Shiono, Phytochemistry Letters, Volume 54, April 2023, Pages 32-39

3. Integracide derivatives produced by endophyte Fusarium armeniacum M-3 isolated fromDigitaria ciliaris. Shiho Sato, Ferry Ferdiansyah Sofian, Dradre Atakuru Paulin, Sho Kobayashi, Takuya Koseki, Yoshihito Shiono, Natural Product Research (2023).

2.Nurlelasari, Parulian SS, Naini AA, Hilmayanti E, Farabi K, Harneti D,Darwati, Mayanti T, Maharani R, Herlina T, Supratman U, Anwar R, Fajriah S, AzmiMN, Prescott T, Shiono Y.

Tirucallane-type triterpenoid from the stem bark of Chisocheton lasiocarpus and its cytotoxic activity against MCF-7 breast cancer cells. J Asian Nat Prod Res. 2022 Nov 21:1-7. doi:10.1080/10286020.2022.2143353. Epub ahead of print. PMID: 36409205.

1. Naini AA, Mayanti T, Harneti D, Darwati, Nurlelasari, Maharani R, Farabi K,

Herlina T, Supratman U, Fajriah S, Kuncoro H, Azmi MN, Shiono Y, Jungsuttiwong

S, Chakthong S. Sesquiterpenoids and sesquiterpenoid dimers from the stem bark

of Dysoxylum parasiticum (osbeck) kosterm. Phytochemistry. 2023 Jan;205:113477.

doi: 10.1016/j.phytochem.2022.113477. Epub 2022 Oct 22. PMID: 36283447.


2022

15.New Ergostane-type Sterol Produced by an Endophytic Fungus Fusarium phaseoli Isolated from Chisocheton macrophyllus (Meliaceae), Records of Natural Products, 2022,16:6, 614-621.

14.Afifah Zahra Agista, Sharon Angela Tanuseputero, Takuya Koseki, Ardiansyah, Slamet Budijanto, Halima Sultana, Yusuke Ohsaki, Chiu-Li Yeh, Suh-Ching Yang, Michio Komai, Hitoshi Shirakawa, Tryptamine, a microbial metabolite in fermented rice bran suppressed lipopolysaccharide-induced inflammation in a murine macrophage model. International Journal of Molecular Sciences, 23 (2022) 11209. https://doi.org/10.3390/ijms231911209

13. Farabi K, Harneti D, Darwati, Mayanti T, Nurlelasari, Maharani R, Sari AP, Herlina T, Hidayat AT, Supratman U*, Fajriah S, Azmi MN, Shiono Y. 

Dammarane-TypeTriterpenoid from the Stem Bark of Aglaia elliptica (Meliaceae) and Its Cytotoxic Activities. Molecules. 2022 Oct 10;27(19):6757. 

12. Nanoparticulate System for the Transdermal Delivery of Catechin as an Antihypercholesterol: In Vitro and In Vivo Evaluations.Mita SR, Abdassah M, Supratman U, Shiono Y, Rahayu D, Sopyan I, Wilar G.Pharmaceuticals (Basel). 2022 Sep 13;15(9):1142. doi: 10.3390/ph15091142.PMID: 36145363

11. 小関卓也 (2022): 麹菌からのフラボノイド配糖体から二糖を遊離させる加水分解酵素, 発酵・醸造食品の最前線㈼, 北本勝ひこ監修, シーエムシー出版, pp127-132.

10.Mutational analysis of the effects of N-glycosylation sites on the activity and thermal stability of rutinosidase from Aspergillus oryzae

Takuya Koseki, Naoki Ishida, Ruka Hirota, Yoshihito Shiono, Koki Makabe

Enzyme and Microbial Technology, 161 (2022) 110112.

9.New dammarane-type triterpenoids from Aglaia elliptica (C.DC.) Blume,

8.Tridysoxyphenols A and B, two new trimeric sesquiterpene phenols from Dysoxylum parasiticum leaves

Ferry Ferdiansyah Sofian, Anas Subarnas, Mayuka Hakozaki , Shota Uesugi, TakuyaKoseki, Yoshihito Shiono

Phytochemistry Letters, Volume 50, August 2022, Pages 134-140

7. Structure elucidation of a new bicoumarin derivative from the leaves of Dysoxylum parasiticum (Osbeck) Kosterm.

Ferry Ferdiansyah Sofian, Anas Subarnas, Takuya Koseki, Yoshihito Shiono. Magnetic Resonance in Chemistry, First published: 18 March 2022

6. Bidysoxyphenols A-C, dimeric sesquiterpene phenols from the leaves of Dysoxylum parasiticum (Osbeck) Kosterm, Ferry Ferdiansyah Sofian, Anas Subarnas, Mayuka Hakozaki, Shota Uesugi, Takuya Koseki, Yoshihito Shiono, Fitoterapia, Volume 158, April 2022, 105157

5. Limonoids from the fruits of Chisocheton lasiocarpus (Meliaceae)

Dewa Gede Katja, Erina Hilmayanti, Nurlelasari, Tri Mayanti, Desi Harneti, Rani Maharani, Kindi Farabi, Darwati, Ronny Lesmana, Sofa Fajriah, Unang Supratman, Mohamad Nurul Azmi & Yoshihito Shiono (2022): Journal of Asian Natural Products Research, DOI: 10.1080/10286020.2022.2032678

4. Petasin is the main component responsible for the anti-adipogenic effect of Petasites japonicus

Shota Uesugi, Mayuka Hakozaki, Yuko Kanno, Akiko Shiraishi, Mizuki Suzuki, Ken-ichi Kimura,  Yoshihito Shiono , Akira Yano. Fitoterapia Accepted (2022).


3. J. Islam, A. Z., Agista, K. Watanabe, T. Nochi, H. Aso, Y. Ohsaki, T. Koseki, M. Komai, H. Shirakawa, 

Fermented rice bran supplementation attenuates chronic colitis-associated extraintestinal manifestations in female C57BL/6N mice. 

Journal of Nutritional Biochemistry, 99, 108855 (2022). https://doi.org/10.1016/j.jnutbio.2021.108855

2. Antioxidant p-Terphenyl Compound, Isolated from Edible mushroom, Boletopsis leucomelas (Pers.) Fayod

Ferry Ferdiansyah Sofian, Nodoka Kikuchi, Takuya Koseki, Yuko Kanno, Shota Uesugi, Yoshihito Shiono

Bioscience, Biotechnology, and Biochemistry Accepted (2022). 

1. Cytotoxic sesquiterpenoids from Dysoxylum parasiticum (Osbeck) Kosterm. stem bark

Al Arofatusnaini, Tri Mayanti, Nurlelasari, Desi Harneti a, Rani Maharani, Agus Safari, Ace Tatang Hidayata,c, Kindi Farabi, Ronny Lesman, Unang Supratman*,
Yoshihito Shiono

Phytochemistry Letters 47 (2022) 102-106

2021

14. Ferry Ferdiansyah Sofian, Takuma Suzuki, Unang Supratman, Desi Harneti, Rani Maharani, Supriatno Salam, Fajar Fauzi Abdullah, Jun Yoshida, Yoshiaki Ito, Takuya Koseki, Yoshihito Shiono

The 2,3-epoxy naphthoquinol produced by endophyte  Arthrinium marii M-211

Natural Product Research (2021).

13. Ferry Ferdiansyah Sofian, Takuma Suzuki, Unang Supratman, Desi Harneti, RaniMaharani, Supriatno Salam, Fajar Fauzi Abdullah, Takuya Koseki, Kurumi Tanaka, Ken-ichi Kimura, Yoshihito Shiono

Cochlioquinone derivatives produced by coculture of endophytes, Clonostachys rosea and Nectria pseudotrichia, Fitoterapia (2021)

12. Tomoe Kato, Yoshihito Shiono , Takuya Koseki. 

Identification and characterization of an acetyl xylan esterase from Aspergillus oryzae. 

J Biosci Bioeng, 2021 Aug 7;S1389-1723(21)00177-8. doi: 10.1016/j.jbiosc.2021.06.014. 

11. Makabe K, Hirota R, Shiono Y, Tanaka Y, Koseki T.

Aspergillus oryzae Rutinosidase: Biochemical and Structural Investigation.

Applied and Environmental Microbiology, 87(3), e02438-20 (2021). https://doi.org/10.1128/AEM.02438-20

10. A. Z. Agista, T. B. Rusbana, J. Islam, Y. Ohsaki, H. Sultana, R. Hirakawa, K. Watanabe, T. Nochi, Ardiansyah, S. Budijanto, S.-C. Yang, T. Koseki, H. Aso, M. Komai, H. Shirakawa. 

Fermented rice bran supplementation prevents the development of intestinal fibrosis due to DSS-induced inflammation in mice. 

Nutrients, 13, 1869 (2021).

9. 小関卓也, 醸造で重要な酵素1-アミラーゼなど, 醸造の事典, 北本勝ひこ・大矢禎一・後藤奈美・五味勝也・高木博史編, 朝倉書店, pp74-77 (2021).

8. Asperpyrone, a rare α-pyrone metabolite produced by an endophytic fungus Aspergillussp. isolated from Garicinia smeathmannii (Planch. & Triana).

Oliv.Jouda JB, Njoya EM, Nguengang RT, Tankeu VFT, Stammler HG, Shiono Y, Sewald N, Lannang AM. 

Nat Prod Res. 2021 Jun 28:1-8. doi: 10.1080/14786419.2021.1944139. Online ahead of print.PMID: 34180309

7. Phytotoxic β-resorcylic acid derivatives from the endophytic fungus Lasiodiplodia theobromae in the mangrove plant

Yoshihito Shiono, Shiho Sato, Ferry Ferdiansyah Sofiana, Takuya Koseki, Fajar Fauzi, Abdullah, Supriatno Salam, Desi Harneti, Rani Maharani, Unang Supratman, Phytochemistry Letters, Volume 44, August 2021, Pages 1-6

6.Two new octahydronaphthalene derivatives, trichodermic acid C and D produced by Trichoderma sp. HN-1.1

Ferry Ferdiansyah Sofiana, Fatimah Ayu Warahapsari, Jun Yoshida, Yoshiaki Ito, Takuya Koseki, Yoshihito Shiono, Natural product research, (2021).

5. Polyacanthosides B and C, two new triterpenoid saponins from the roots of Acacia polyacantha (Mimosaceae)

Abdou Tchoukoua, Sandrine Carole Tomfeun Nganou, Dabole Bernard,a Jun Yoshida, Yoshiaki Ito, Bonaventure Tchaleu Ngadjui, Yoshihito Shiono,

Phytochem. Lett. (2021).

4. Cytotoxic triterpenoids from Chisocheton pentandrus

Supriatno Salam, Desi Harnetia, Rani Maharani, Nurlelasari, Agus Safari, Ace Tatan, Hidayata, Ronny Lesman, Mohamad Azlan Nafia, Unang Supratman, Thomas Alexander Kyle Prescott, Yoshihito Shiono

Phytochemistry Phytochemistry 187 (2021) 112759.

3. A new havanensin-type limonoid from Chisocheton macrophyllus

Nurlelasari, Intan Rahmayanti, Supriatno Salam, Agus Safari, Desi Harneti, Rani Maharani, Ace Tatang Hidayat, Mulyadi Tanjung, Rurini Retnowati, Yoshihito Shiono & Unang Supratman

Applied Biological Chemistry, 64,  (2021) Applied Biological Chemistry.  

2. Triterpene saponins from Acacia senegal (L.) Willd and cytotoxic effect in H4IIE cells

Abdou Tchoukoua,  Mireille Heti Douanla, Nanang Rudianto Ariefta, Jun

Yoshida, Yoshiaki Ito, Bonaventure Tchaleu Ngadjui, Yoshihito Shiono, Fitoterapia 2021.

1. β‐Resorcylic Acid Derivatives, with Their Phytotoxic Activities, from the Endophytic Fungus Lasiodiplodia theobromae in the Mangrove Plant Xylocarpus granatum

Shiho Sato, Ferry Ferdiansyah Sofian, Wataru Suehiro, Desi Harneti, Rani Maharani, Unang Supratman, Fajar Fauzi Abdullah, Supriatno Salam, Takuya Koseki, Yoshihito Shiono.Chemistry&Biodiversity, 8 February 2021.

2020

16. Spirocollequins A and B, new alkaloids featuring a spirocyclic isoindolinone core, from Colletotrichum boninense AM-12-2. Nanang Rudianto Ariefta, Takuya Koseki, Yoshifumi Nishikawa, Yoshihito Shiono, Tetrahedron Letters,  19 December 2020, 152736

15. Tubagus Bahtiar Rusbana, Afifah Zahra Agista, Wahyu Dwi Saputra, Yusuke Ohsaki, Kouichi Watanabe, Ardy Ardiansyah, Slamet Budijanto, Takuya Koseki, Hisashi Aso, Michio Komai, Hitoshi Shirakawa, Supplementation with fermented rice bran attenuates muscle atrophy in a diabetic rat model. Nutrients, 12(8), 2409 (2020). https://doi.org/10.3390/nu12082409

14.K. Ichikawa, A. Yoshida, Y. Shiono, T. Koseki, Biochemical characterization of a lipolytic enzyme from Aspergillus oryzae that hydrolyzes triacylglycerol and sterol esters. Applied Biochemistry and Biotechnology, 192, 910-922 (2020) https://doi.org/10.1007/s12010-020-03360-4

13. A new chromene derivative and a new polyalcohol isolated from the fungus Xylaria sp. 111A associated with Garcinia polyantha leaves.

Natural Product Communications, 2020.

12. Heptacyclosordarianone, a New Polyketide From Sordaria sp., an Endophytic Fungus From Garcinia polyantha

Virginie Flaure Tsague Tankeu, Denis Kehdinga Sema, Jean-Bosco Jouda, Simplice Joel N. Tatsimo, Patrick Akono Ntonga, Jean Duplex Wansi, Simeon Kouam Fogue, Benoît Loura, Yoshihito Shiono, Norbert Sewald, Alain Meli Lannang

Natural Product Communications, vol. 15, 12, First Published December 16, 2020.


11. Phytotoxic compounds isolated from a sea snail derived fungus, Penicillium vancouverense YY-1

Author links open overlay panel. Yasuhiro Yokoyama, Takuya Koseki, Desi Harneti, Rani Maharani, Unang Supratman, Yoshihito Shiono, Phytochemistry LettersVolume 39, October 2020, Pages 57-63.

10. Constituents of the Fruiting Body of Poisonous Mushroom Omphalotus japonicus.

Aoki S, Aboshi T, Shiono Y, Kimura KI, Murata T, Arai D, Iizuka Y, Murayama T*.

Chem Pharm Bull (Tokyo). 2020;68(5):436-442. doi: 10.1248/cpb.c19-01009.

9. Antibacterial and herbicidal properties of secondary metabolites from fungi

Mona M. G. Saad, Samir A. M. Abdelgaleil, Yoshihito Shiono

Natural Product Research, 2020, Published online: 22 Jun 2020.

8. Cytotoxic triterpenoids from the stem bark of Aglaia angustifolia. Ricson Pemimpin Hutagaol, Desi Harneti, Agus Safari, Ace Tatang Hidayat, Unang Supratman, Khalijah Awang & Yoshihito Shiono. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH https://doi.org/10.1080/10286020.2020.1776704

7. New Compounds from Japanese Oak Wilt Disease-associated fungus Raffaelea quercivora

Tomoki Nakamura, Unang Supratman, Desi Harneti, Rani Maharani, Takuya Koseki, Yoshihito Shiono*. 2020. Natural Product Research. in press.

6. Colletofurans A-E, 1-Octyl-1,3-dihydroisobenzofuran Derivatives from Colletotrichum boninense AM-12-2. Nanang R. Ariefta, Muhlisun Azim, Takako Aboshi, Takuya Koseki, Yoshimasa Taniguchi, Makoto Fujita, Yoshihito Shiono*. Organic Letters,  March 27, 2020

5. Identification of flavonoid compounds from ethyl acetate extract of Kalanchoe millotii (Crassulaceae) and endodontics antibacterial activity. Yenny Febriani Yun*, Issana Pramordha Wardhani, Nurhabibah Alawiyah, Dewi Meliati Agustini, Lilis Siti Aisyah, Sari Purbaya, Unang Supratman and Yoshihito Shiono, 53-55. (2020).Research Journal of Chemistry and Environment.

4. (22E,24S)-24-Propylcholest-5en-3α-acetate: A New Steroid from the Stembark Aglaia angustifolia (Miq.) (Meliaceae). Ricson P. Hutagaol, Desi Harneti, Ace T. Hidayat, Nurlelasari , Rani Maharani, Dewa Gede Katja, Unang Supratman*, Khalijah Awang and Yoshihito Shiono. Molbank, 2020(1), M1112; https://doi.org/10.3390/M1112.

3. Efficient production of a recombinant tannase in Aspergillus oryzae using an improved glucoamylase gene promoter.

Kyotaro Ichikawa, Yoshihito Shiono, Tomoko Shintani, Akira Watanabe, Hiroshi Kanzaki, Katsuya Gomi, Takuya Koseki*. Journal of Bioscience and Bioengineering. 2020, Pages 150-154

2. Antimicrobial and phytotoxic activities of secondary metabolites from 2 Haplophyllum tuberculatum and Chrysanthemum coronarium.  Samir A. M. Abdelgaleil,* Mona M. G. Saad, Nanang R. Ariefta , Yoshihito Shiono. South African Journal of Botany 128 (2020) 35-41.

 1New Cytotoxic Limonoids from the Stem Bark of Chisocheton pentandrus (Meliaceae)

Unang Supratman, Supriatno Salam, Wiro Naibaho, Mohamad Fajar, Nurlelasari, Dewa Gede Katja, Desi Harneti, Rani Maharani, Ace Tatang Hidayat, Ronny Lesmana, and Yoshihito Shiono. Phytochemistry Letters , 35, 63-67. DOI: 10.1016/j.phytol.2019.11.002

2019

10. Fusopoltides B-E, new polyketides isolated from Fusarium solani B-18

Nanang Rudianto Ariefta, Hasna Tazkia Nikmawahda, Takuya Koseki

Yoshihito Shiono. Tetrahedron Lett. Accepted.

9. New Metabolites Produced by endophyte Bionectria ochroleucaB5−2

UnangSupratman, Takuma Suzuki, Tomoki Nakamura, Yasuhiro Yokoyama, Desi Harneti, Rani Maharani, Supriatno Salam, Fajar Fauzi Abdullah, Takuya Koseki, Yoshihito Shiono*. Nat Prod Res. 2019

8. New naphthoquinone derivatives from Fusarium napiforme of a mangrove plant

Unang Supratman, Nami Hirai, Shiho Sato, Keiko Watanabe, Abdul Malikc, Suwardi Annas, Desi Harneti, Rani Maharani, Takuya Koseki, Yoshihito Shiono*. Nat Prod Res. 2019

7. A new antiplasmodial sterol from Indonesian marine sponge, Xestospongia sp.

Murtihapsari M, Salam S, Kurnia D, Darwati D, Kadarusman K,  Abdullah FF, Herlina T, Husna MH, Awang K, Shiono Y, Azmi MN, Supratman U. Nat Prod Res. 2019. doi.org/10.1080/14786419.2019.1611815

6. 小関卓也, フラボノイド配糖体から二糖を遊離させる糸状菌由来加水分解酵素,バイオサイエンスとインダストリー, 77, 51-52 (2019)

5. Meroterpenoids Produced by Pseudocosmosporasp. Bm-1-1 Isolated from Acanthus ebracteatus Vahl

Tomoki Nakamura, Takuma Suzuki, Nanang Rudianto Ariefta, Takuya Koseki, Takako Aboshi, Tetsuya Murayama, Ari Widiyantoro, Rikhsan Kurniatuhadi, Abdul Malik,Suwardi Annas, Desi Harneti, Rani Maharani, Unang Supratman, Junpei Abe, Naoaki Kurisawa, Ken-ich Kimura, Yoshihito Shiono,* Phytochemistry Letters, (2019) accepted.

4. Triterpenoids from the Bark of Aglaia Glabrata and Their In Vitro Effects on P-388 Murine Leukemia Cells. Desi Harneti, Asep Supriadin, Rani Maharani, Nurlelasari, Tri Mayanti, Ace Tatang Hidayat, Risyandi Anwar, Unang Supratman*, Khalijah Awang and Yoshihito Shiono. Oriental Journal of Chemistry 35(1):134-139, (2019).

3. Cytotoxic Triterpenoids from the Bark of Chisocheton patens Blume (Meliaceae)

Unang Supratman*, Ace Hidayat, Desi Harneti, Nurlelasari Nurlelasari, Rani Maharani, Supriatno Salam, Wiro Naibaho, Yoshihito Shiono. Phytochemistry Letters, (2019) 30:81-87.

2. Fusaspirols A-D, novel oxaspirol derivatives isolated from Fusarium solani B-18

Nanang Rudianto Ariefta*, Hasna Tazkia Nikmawahdab, Takako Aboshi, Tetsuya Murayama, Keitaro Tawaraya, Takuya Koseki, Genta Katagi, Yoshito Kakihara, Yoshihito Shiono*, Tetrahedron, (2019), 75, 11371-1377.

1. New Polyketides, Paralactonic Acids A-E Produced by Paraconiothyrium sp. SW-B-1, An Endophytic Fungus Associated with A Seaweed, Chondrus ocellatus Holmes . Takuma Suzuki, Nanang Rudianto Ariefta, Takuya Koseki, Hiroshi Furuno, Eunsang Kwon, Hiroyuki Momma, Desi Harneti, Rani Maharani, Unang Supratman, Ken-ichi Kimura, Yoshihito Shiono*, Fitoterapia, 132, 75-81, (2019)


2018

11. Characterization of a novel Aspergillus oryzae tannase expressed in Pichia pastoris 

Takuya Koseki*, Kyotaro Ichikawa, Katsuto Sasaki, Yoshihito Shiono, Journal of Bioscience and Bioengineering, 126, (2018), 553-558. 

10.(Mini Review )β-Diglycosidases from microorganisms as industrial biocatalysts: biochemical characteristics and potential applications. Applied Microbiology and Biotechnology. T. Koseki* , M. Ishikawa, M. Kawasaki, Y. Shiono. 2018.  Applied Microbiology and Biotechnology, 100: 8717-8723.

9. Lambertellin from Pycnoporus sanguineus MUCL 51321 and its anti-inflammatory effect via modulation of MAPK and NF-κB signaling pathways. Jean-Bosco Jouda, Emmanuel Mfotie Njoya, Céline Djama Mbazoa, ZongYuan Zhou, Alain Meli Lannang*, Jean Wandji, Yoshihito Shiono, Fei Wang*, (2018). Bioorganic Chemistry, in press.

8.DAMMARANE-TYPE TRITERPENOIDS FROM THE STEMBARK OF AGLAIA ARGENTEA (MELIACEAE)  Ace Tatang Hidayat, Kindi Farabi, Ida Nur Farida, Kansy Haikal, Nurlelasari Nurlelasari, Desi Harneti Putri Huspa, Rani Maharani, Unang Supratman*, Yoshihito Shiono,  Jurnal Kimia VALENSI Volume 4, No. 1, Mei 2018 (Indonesia).

7. A pyrrocidine derivative produced by fungus Neonectria ramulariae In-2 isolated from a Beetle Holotrichia picea. Yoshihito Shiono*, Mariko Furukawa, Takuya Koseki , Eunsang Kwon, Andreas Hendracipta Kurniawan, Satoru Sato, Desi Harneti, Rani Maharani, Unang Supratman, Shota Uesugi , Ken-ichi Kimura (2018)Phytochemistry Letters, 26, 120-124

6. Nanang Rudianto Ariefta, Priska Kristiana , Takako Aboshi , Tetsuya Murayama , Keitaro Tawaraya, Takuya Koseki , Naoaki Kurisawa , Ken-ichi Kimura, Yoshihito Shiono*.  (2018). New isocoumarins, naphthoquinones, and a cleistanthane-type diterpene from Nectria pseudotrichia 120-1NP. Fitoterapia. 127, 356-361.

5.  Mai Ishikawa1, Mayu Kawasaki1, Yoshihito Shiono, Takuya Koseki* (1 Equal contribution). (2018). A novel Aspergillus oryzae diglycosidase that hydrolyzes 6-O-α-L-rhamnosyl-β-D-glucoside from flavonoids. Applied Microbiology and Biotechnology. 102, 3193-3201. 

4. Takuma Suzuki, Seiya Yoshida, Takuya Koseki, Takako Aboshi, Tetsuya Murayama, Unang Supratman, Yoshihito Shiono*. (2018). New Metabolites Produced by Cylindrocarpon sp. SY-39 from a Driftwood.  CHEMISTRY & BIODIVERSITY, 15. https://doi.org/10.1002/cbdv.201700493.

3.  A. Tchoukoua, Turibio Kuiate Tabopda*, N. Usukhbayar, K. Kimura, E.  Kwon, H. Momma, T.  Koseki, Y.  Shiono*, B. T. Ngadjui*.  (2018). New Triterpene saponins from the stem of Acacia kamerunensis (Mimosaceae).  Phytochemistry Letters, 2018, 23, 21-25.

2. Supriatno, Nurlelasari, Tati Herlina, Desi Harneti, Rani Maharani, Ace Tatang Hidayat, Tri Mayanti, Unang Supratman*, Mohamad Nurul Azmi and Yoshihito Shiono.  A New Limonoid from Stem Bark of Chisocheton pentandrus (Meliaceae). Nat. Prod. Res. 32. 2018. https://doi.org/10.1080/14786419.2018.1428600

1. Yoshihito Shiono*, Takuya Koseki, Hiromasa Koyama. A Bioactive Depsidone from Lachnum virgineum (Hyaloscyphaceae). Natural Product Sciences. 24: 79-81 (2018).


2017

1. J. Islam, T. Koseki, K. Watanabe, Ardiansyah, S. Budijant, A. Oikawa, M.Alauddin, T. Goto, H. Aso, M. Komai, H. Shirakawa, (2017). Dietary supplementation of fermented rice bran effectively alleviates dextran sodium sulfate-induced colitis in mice. Nutrients, 9, 747 (2017). Doi: 10.3390/nu9070747.

2. D. Komiya, A. Hori, T. Ishida, K. Igarashi, M. Samejima, T. Koseki, S. Fushinobu, Crystal structure and substrate specificity modification of acetyl xylan esterase from Aspergillus luchuensis.        Applied and Environmental Microbiology, 83, e01251-17 (2017). Doi: 10.1128/AEM.01251-17.

3.  M. Ishikawa, Y. Shiono, T. Koseki, (2017). Biochemical characterization of Aspergillus oryzae recombinant α-L-rhamnosidase expressed in Pichia pastoris.       Journal of Bioscience and Bioengineering, 124, 630-634. Doi: 10.1016/j.jbiosc.2017.07.007.

4.  M. Alauddin, J. Islam, H. Shirakawa, T. Koseki, Ardiansyah and M. Komai (2017).   Rice Bran as a Functional Food: An Overview of the Conversion of Rice Bran into a Superfood/Functional Food. In: Superfood and Functional Food - An Overview of Their Processing and Utilization (Ed. V. Waisundara and N. Shiomi), InTech, p291-305. DOI: 10.5772/66298.

5.Tchoukoua, A., Suzuki, T., Ariefta, N. R., Koseki, T., Okawa, Y., Kimura, K.-I., Shiono, Y., (2017).   A new eremophilane sesquiterpene from the fungus Xylaria sp. V-27 and inhibition activity against degranulation in RBL-2H3 cells.  J. Antibiotics. 70, 1129-1132.

6. Tchoukoua, A., Hasegawa, R., Hendracipta, K. A., Sato, S., Koseki, T., Shiono, Y., 2018. Structure elucidation of new fusarielins from Fusarium sp. and their antimicrobial activity. Magn. Reson. Chem., 56, 32-36. doi: 10.1002/mrc.4662. 

7. Y. Shiono, N.I. Muslihah, T. Suzuki, N.R. Ariefta, C. Anwar, H.H. Nurjanto, Takako Aboshi, T. Murayama, K. Tawaraya, T. Koseki, J. Yoshida, N. Usukhbayar, Shota Uesugi, K. Kimura (2017). New Eremophilane and Dichlororesorcinol Derivatives Produced by Endophytes Isolated from Ficus ampelas. J. Antibiot. 70, 1133-1137.

8. Lilis Siti Aisyah, Yenny Febriani Yun,1 Tati Herlina, Euis Julaeha, Achmad Zainuddin, Ida Nurfarida, Ace Tatang Hidayat, Unang Supratman, and Yoshihito Shiono. (2017). Flavonoid Compounds from the Leaves of Kalanchoe prolifera and Their Cytotoxic Activity against P-388 Murine Leukimia Cells. Nat Prod Sci. 23(2):139-145.

9. Kindi Farabi, Desi Harneti, Nurlelasari, Rani Maharani, Ace Tatang Hidayat, Khalijah Awang, Unang Supratman, Yoshihito Shiono. 2017. New cytotoxic protolimonoids from the stem bark of Aglaia argentea (Meliaceae) Phytochemistry Letters, Volume 21, 211-215

10.  Lannang AM, Sema DK, Tatsimo SJN, Tankeu VFT, Tegha HF, Wansi JD, Shiono Y, Sewald N. (2017).   A new depsidone derivative from the leaves of Garcinia polyanthus. Nat Prod Res. 2017 Sep 20:1-6. doi:10.1080/14786419.2017.1378201.

11.  Yoshida S, Suzuki T, Furuno H, Aboshi T, Murayama T, Koseki T, Shiono Y. (2018). Spectroscopic characterisation of two polyketide metabolites from Cylindrocarpon sp. from driftwood.  Nat Prod Res. 2018, 32:60-64. doi: 10.1080/14786419.2017.1332616.

12.  Fotso GW, Kamga J, Ngameni B, Uesugi S, Ohno M, Kimura KI, Momma H, Kwon E, Furuno H, Shiono Y, Ingrid SK, Yeboah SO, Ngadjui BT. (2017).  Secondary metabolites with antiproliferative effects from Albizia glaberrima var glabrescens Oliv. (Mimosoideae).   Nat Prod Res. 31, 1981-1987. doi:10.1080/14786419.2016.1269097.

13. Quach HT, Tanigaki R, Yokoigawa J, Yamada Y, Niwa M, Hirano S, Shiono Y, Kimura KI, Kataoka T. (2017) . Allantopyrone A interferes with multiple components of the TNF receptor 1 complex and blocks RIP1 modifications in the TNF-α-induced signaling pathway.   J. Antibiot (Tokyo). 2017 Aug;70(9):929-936. doi: 10.1038/ja.2017.74.

14.   Tchoukoua A, Tabopda TK, Usukhbayar N, Kimura KI, Kwon E, Momma H, Koseki T, Shiono Y,  Ngadjui BT.  New triterpene saponins from the roots of Acacia macrostachya (Mimosaceae).  Biosci Biotechnol Biochem.81, 2261-2267. doi: 10.1080/09168451.2017.1390393 

15. N. R. Ariefta, P. Kristiana, H.H. Nurjanto, H. Momma, E. Kwon, T. Ashitani, K. Tawaraya, T. Murayama, T. Koseki, H. Furuno, N. Usukhbayar, K. Kimura, Y. Shiono (2017). Nectrianolins A, B, and C, new metabolites produced by endophytic fungus Nectria pseudotrichia 120-1NP.    Tetrahedron Lett. 58, 4082-4086.

16.Tchoukoua, A., Tabopda, T. K., Uesugi, S., Ohno, M., Kimura, K.-I., Kwon, E., Momma, H., Horo, I., Çalişkan, O. A., Shiono, Y., Ngadjui, B. T., (2017). Triterpene saponins from the roots of Acacia albida Del. (Mimosaceae). Phytochemistry, 136, 31-38.

17.Tchoukoua, A., Ota, T., Akanuma, R., Ju, Y.-M., Supratman, U., Murayama, T., Koseki, T., Shiono, Y., (2017). A phytotoxic bicyclic lactone and other compounds from endphyte Xyalria curta.   Nat. Prod. Res., 31, 2113-2118.

18.Tchoukoua, A., Tabopda, T. K., Simo, I. K., Uesugi, S., Ohno, M., Kimura, K.-I., Kwon, E., Momma, H., Shiono, Y., Ngadjui, B. T., 2017. Two new triterpene saponins from the barks of Acacia albida Del. (Mimosaceae). Nat. Prod. Res., doi.org/10.1080/14786419.2017.137 1156.

19. Uesugi S, Muroi M, Kondoh Y, Shiono Y, Osada H, Kimura KI. (2017).  Allantopyrone A activates Keap1-Nrf2 pathway and protects PC12 cells from oxidative stress-induced cell death. J Antibiot. 70,429-434.

20. T. Koseki, M. Otsuka, T. Mizuno, Y. Shiono (2017): Mutational analysis of Kex2 recognition sites and a disulfide bond in tannase from Aspergillus oryzae. Biochemical and Biophysical Research Communications, 482, 1165-1169. DOI: 10.1016/j.bbrc.2016.12.006.

21. Kindi Farabi, Desi Harneti, Nurlelasari, Rani Maharani, Ace Tatang Hidayat, Unang Supratman, Khalijah Awang,  Yoshihito Shiono (2017):Cytotoxic Steroids from the Bark of Aglaia argentea (Meliaceae). CMU J. Nat. Sci. 16. 293-306. 

22. Kindi Farabi, Desi Harneti, Nurlelasari, Rani Maharani, Ace Tatang Hidayat, Khalijah Awang, Unang Supratman and Yoshihito Shiono. (2017): New Cytotoxic Pregnane-type Steroid from the Stem Bark of Aglaia elliptica (Meliaceae) .  Rec. Nat. Prod. (2017), 12:2 ; 121-127

23.Takako Aboshi, Shiho Ishiguri, Yoshihito Shiono & Tetsuya Murayama (2018): Flavonoid glycosides in Malabar spinach Basella albainhibit the growth of Spodoptera litura larvae.  Biosci Biotechnol Biochem.  82, 8-14. 

24. Ace Tatang Hidayat, Kindi Farabi, Desi Harneti, Rani Maharani, Darwati, Nurlelasari, Tri Mayanti, Arlette Suzy Setiawan, Unang Supratman*, and Yoshihito Shiono. Cytotoxicity and Structure Activity Relationship of Dammarane-Type Triterpenoids from the Bark of Aglaia elliptica against P-388 Murine Leukemia Cells. Natural Product Sciences. 23(4) : 291-298 (2017). https://doi.org/10.20307/nps.2017.23.4.291


2016

1. M. Alauddin, H. Shirakawa, T. Koseki, N. Kijima, Ardiansyah, S. Budijanto, J. Islam, T. Goto, M. Komai, Fermented rice bran supplementation mitigates metabolic syndrome in stroke-prone spontaneously hypertensive rats. BMC Complementary and Alternative Medicine, 16, 442 (2016).

2. Y. Shiono, N. Miyazaki, T. Murayama, T. Koseki, Harizon, D. G. Katja, U. Supratman, J. Nakata, Y. Kakihara, M. Saeki, J. Yoshida, S. Uesugi, K. Kimura (2016). GSK-3β inhibitory activities of novel dichroloresorcinol derivatives from Cosmospora vilior isolated from a mangrove plant. Phytochemistry Lett. 18, 122-127.

3.  Y. Shiono, N.R. Ariefta, C. Anwar, S. Matsjeh, R. Sappapan, T Murayama, T. Koseki, T. Kawamura, S. Uesugi, K. Kimura. (2016). New metabolites produced by Fusarium solani T-13 isolated from a dead branch. Phytochemistry Lett. 17, 232-237.

4. Tchoukoua, A., Tabopda, T. K., Uesugi, S., Kimura, K.-I., Kwon, E., Momma, H., Ngadjui, B. T., Koseki, T., Shiono, Y., 2016. Two new 5-deoxyflavan-3,4-diol glucosides from roots of Albizia chevialieri. Magn. Reson. Chem., 54, 893-896.

5. S. Uesugi, N. Fujisawa, J. Yoshida, M. Watanabe, S. Dan, T. Yamori, Y. Shiono, K. Kimura. (2016). Pyrrocidine A, a metabolite of endophytic fungi, has a potent apoptosis-inducing activity against HL60 cells through caspase activation via the Michael addition. J Antibiot. 69, 133-40.

6. T. Koseki, H. Handa, Y. Watanabe, M. Ohtsuka, Y. Shiono (2016): An unusual feruloyl esterase from Aspergillus oryzae: two tryptophan residues play a crucial role for the activity. Journal of Molecular Catalysis B: Enzymatic, in press. DOI: 10.1016/j.molcatb.2016.11.008.




発酵制御学、 All rights reserved 2017年
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